AKOS PAO-1009 - Names and Identifiers
AKOS PAO-1009 - Physico-chemical Properties
Molecular Formula | C8H11ClN2O2
|
Molar Mass | 202.64 |
Storage Condition | Room Temprature |
Sensitive | Irritant |
MDL | MFCD03419665 |
AKOS PAO-1009 - Risk and Safety
Hazard Symbols | Xi - Irritant
|
Hazard Class | IRRITANT |
AKOS PAO-1009 - Introduction
3-(4-Chloro-3)-propionic acid, also known as 3-(4-chloro-3, 5-dimethyl-pyrazol-1-yl)-propionic acid. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: White crystalline solid.
-Chemical formula: C9H12ClN3O2.
-Molecular weight: 223.66g/mol.
-Melting point: 160-162°C.
-Solubility: Low solubility in water, soluble in organic solvents such as methanol, ethanol and dichloromethane.
Use:
3-(4-Chloro-3)-propionic acid is often used as a pharmaceutical intermediate. It is widely used in the synthesis of various drugs, especially anti-inflammatory drugs and non-steroidal anti-inflammatory drugs.
Preparation Method:
The synthesis of 3-(4-Chloro-3)-propionic acid generally involves the following steps:
1.4-Chloro -3,5-dimethylpyrazole and bromopropionic acid are reacted to generate 4-chloro -3,5-dimethyl-pyrazol -1-yl-propionic acid.
2. The product is subjected to a hydrolysis reaction to obtain 3-(4-chloro-3, 5-dimethyl-pyrazol-1-yl)-propionic acid.
Safety Information:
There is limited information on the safety of 3-(4-Chloro-3)-propionic acid. The following safety precautions should be followed when using it:
-Avoid contact with skin and eyes. If contact occurs, rinse immediately with plenty of water.
-Use appropriate protective equipment such as lab sheds, protective gloves and goggles for preparation and handling.
-Operate in a well-ventilated place to avoid inhaling dust and steam.
-Store dry, sealed, and away from fire and oxidizing agents.
Please note that this provides only basic information, and specific experimental procedures should follow relevant chemical experimental techniques and safety guidelines.
Last Update:2024-04-09 21:54:55